farnesyltransferase inhibitors

farnesyltransferase inhibitors
Онкология: ингибиторы фарнезилтрансферазы (Вещества, испытываемые в качестве противоопухолевых лекарств.)

Универсальный англо-русский словарь. . 2011.

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  • Farnesyltransferase inhibitor — The farnesyltransferase inhibitors (FTIs) are a class of experimental cancer drugs that target protein farnesyltransferase with the downstream effect of preventing the proper functioning of the Ras (protein), which is commonly abnormally active… …   Wikipedia

  • Farnesyltransferase — is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15 carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four amino acid sequence at the carboxyl terminus of a protein.… …   Wikipedia

  • FNTB — Farnesyltransferase, CAAX box, beta, also known as FNTB, is a human gene.cite web | title = Entrez Gene: FNTB farnesyltransferase, CAAX box, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2342|… …   Wikipedia

  • FNTA — Farnesyltransferase, CAAX box, alpha, also known as FNTA, is a human gene.cite web | title = Entrez Gene: FNTA farnesyltransferase, CAAX box, alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2339|… …   Wikipedia

  • Progeria — Infobox Disease Name = Progeria Caption = DiseasesDB = 10704 ICD10 = ICD10|E|34|8|e|20 ICD9 = ICD9|259.8 ICDO = OMIM = 176670 MedlinePlus = eMedicineSubj = derm eMedicineTopic = 731 MeshID = D011371 Progeria is a condition of early aging [Stedman …   Wikipedia

  • Laminopathy — Normal nuclear lamina (a and b) and mutant nuclear lamina (c and d) from a patient with HGPS, visualized by immunofluorescence note the irregular and bumpy shape of the laminopathic nuclei[1] Laminopathies are a group of rare genetic disorders… …   Wikipedia

  • RRAS — Related RAS viral (r ras) oncogene homolog, also known as RRAS, is a human gene.cite web | title = Entrez Gene: RRAS related RAS viral (r ras) oncogene homolog| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • RHOB — Ras homolog gene family, member B, also known as RHOB, is a human gene.cite web | title = Entrez Gene: RHOB ras homolog gene family, member B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=388| accessdate …   Wikipedia

  • Dextrorotation and levorotation — (also spelled laevorotation)[1] refer, respectively, to the properties of rotating plane polarized light clockwise (for dextrorotation) or counterclockwise (for levorotation), seen by an observer whom the light is approaching. A compound with… …   Wikipedia

  • BMS-214662 — A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors …   English dictionary of cancer terms

  • R115777 — A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. Also called tipifarnib and Zarnestra …   English dictionary of cancer terms


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